Vitamin D influences more than 200 genes. This includes genes related
to cancer and autoimmune diseases like multiple sclerosis.
Vitamin D affects your DNA through the vitamin D receptors (VDRs), which
bind to specific locations of the human genome.
Reuters reports:
“Vitamin D deficiency is a well-known risk factor for rickets, and some
evidence suggests it may increase susceptibility to autoimmune diseases
such as multiple sclerosis (MS), rheumatoid arthritis and type 1
diabetes, as well as certain cancers and even dementia.”
Reuter’s information is actually a bit misleading as other
scientists have identified a total of nearly 3,000 genes that are
upregulated by vitamin D. The particular study referenced above
identified 200 genes affected, but it’s not clear if that is in addition
to the ones already identified, or if they simply confirmed many of the
ones found by others.
One thing’s for sure: Vitamin D is one of the major keys for disease
prevention and for optimal health.
The Astonishing Power of Vitamin D to Transform Your Health
In recent years vitamin D has emerged as a star of the “vitamin” world.
For example, there are currently over 800 studies showing vitamin D’s
effectiveness against cancer. Optimizing your vitamin D levels can
literally cut your risk of several cancers by 50 percent!
Further, middle aged and elderly people with high levels of vitamin D
could reduce their chances of developing heart disease or diabetes by 43
percent.
How Does Vitamin D Do What it Does?
Vitamin D is actually a “prohormone,” which your body produces from
cholesterol. Because it is a prohormone, vitamin D influences your
entire body -- receptors that respond to the vitamin have been found in
almost every type of human cell, from your brain to your bones.
So what modern science has now realized is that vitamin D does more than
just aid in the absorption of calcium and bone formation, it is also
involved in multiple repair and maintenance functions, touches thousands
of different genes, regulates your immune system, and much, much more.
Just one example of an important gene that vitamin D up-regulates is
your ability to fight infections, as well as chronic inflammation. It
produces over 200 anti microbial peptides, the most important of which
is cathelicidin, a naturally occurring broad-spectrum antibiotic.
This is one of the explanations for why it’s so effective against colds
and influenza.
In addition, since vitamin D also modulates (balances) your immune
response, it can prevent an overreaction in the form of inflammation,
which can lead to a variety of autoimmune disorders, such as Crohn’s
disease for example.
When you consider the fact that you only have about 25,000 genes in your
body, and vitamin D has been shown to influence nearly 3,000 of them,
the bigger picture of its true impact on your health can be easily
understood.
It may, in fact, have literally thousands of health benefits!
However, it’s also very clear that unless you have taken specific
measures to address it, the odds are overwhelming that you are deficient
in this important nutrient.
Are You Vitamin D Deficient?
Vitamin D deficiency is a growing epidemic across the world and is
contributing to many chronic debilitating diseases. There are a few
reasons for this trend.
First, most people spend far too much time indoors during daytime hours.
You may also have also been seriously misled by “expert’”
recommendations to avoid all sun exposure, and to slather yourself with
sunscreen whenever you do go outside. Please understand that sunscreen
will virtually eliminate your body’s ability to produce any vitamin D
because it blocks the UVB radiation that causes your skin to produce it
naturally.
As a result, in the United States the late winter average vitamin D is
only about 15-18 ng/ml, which is considered a very serious deficiency
state.
In fact, new studies show that about 85 percent of the U.S. population
is vitamin D deficient. This is primarily related to the recent
appreciation that your levels of vitamin D should be MUCH higher than
previously thought.
Consider the following vitamin D facts:
* Vitamin D deficiency is epidemic in adults of all ages who have
increased skin pigmentation, such as those whose ancestors are from
Africa, the Middle East, or India, who always wear sun protection, or
who limit their outdoor activities.
* African Americans and other dark-skinned people and those living in
northern latitudes make significantly less vitamin D than other groups.
* 60 percent of patients with type 2 diabetes have vitamin D deficiency.
* Studies showed very low levels of vitamin D among children, the
elderly, and women.
* One nationwide study of women revealed that almost half of the African
American women of childbearing age might be vitamin-D deficient.
Winter, when sun exposure is at its lowest, is the time of year when you
need to be most concerned about the amount of vitamin D you are
receiving, as your vitamin D levels can drop by up to 50 percent in the
winter.
Of course, if you have the tendency to spend the summer months indoors,
out of the sun, or you only go outside with sunscreen on, then you would
need to be concerned during the summer months as well.
The Many Health Benefits of Vitamin D
It’s absolutely tragic that dermatologists and sunscreen manufacturers
have done such a thorough job of deterring people from the sun -- your
optimal source for natural vitamin D.
Their widely dispersed message to avoid the sun as much as possible,
combined with an overall cultural trend of spending more time indoors
during both work and leisure time, has greatly contributed to the
widespread vitamin D deficiency seen today -- which in turn is fueling
an astonishingly diverse array of common chronic diseases, including:
A study by Dr. William Grant, Ph.D., internationally recognized research
scientist and vitamin D expert, found that about 30 percent of cancer
deaths -- which amounts to 2 million worldwide and 200,000 in the United
States -- could be prevented each year with higher levels of vitamin D.
Other studies showed that you can decrease your risk of cancer by more
than half simply by optimizing your vitamin D levels with sun exposure.
Vitamin D has a protective effect against cancer in several ways,
including:
* Increasing the self-destruction of mutated cells (which, if allowed to
replicate, could lead to cancer)
* Reducing the spread and reproduction of cancer cells
* Causing cells to become differentiated (cancer cells often lack
differentiation)
* Reducing the growth of new blood vessels from pre-existing ones, which
is a step in the transition of dormant tumors turning cancerous
Vitamin D Against Cancer
A study by Dr. William Grant, Ph.D., internationally recognized research
scientist and vitamin D expert, found that about 30 percent of cancer
deaths -- which amounts to 2 million worldwide and 200,000 in the United
States -- could be prevented each year with higher levels of vitamin D.
Other studies showed that you can decrease your risk of cancer by more
than half simply by optimizing your vitamin D levels with sun exposure.
Vitamin D has a protective effect against cancer in several ways,
including:
* Increasing the self-destruction of mutated cells (which, if allowed to
replicate, could lead to cancer)
* Reducing the spread and reproduction of cancer cells
* Causing cells to become differentiated (cancer cells often lack
differentiation)
* Reducing the growth of new blood vessels from pre-existing ones, which
is a step in the transition of dormant tumors turning cancerous
When is the Best Time to Go Out in the Sun, and for How Long?
The optimal time to be in the sun for vitamin D production is as near to
solar noon as possible. That would be between roughly 10:00am and
2:00pm.
During this time you need the shortest exposure time to produce vitamin
D because UVB rays are most intense at this time. Plus, when the sun
goes down toward the horizon, the UVB is filtered out much more than the
dangerous UVA.
When you’re out in the sun, be very careful about the length of your
exposure. You only need enough exposure to have your skin turn the
lightest shade of pink. This may only be a few minutes for some.
Exposures any longer than this will not produce any more vitamin D but
will accelerate photo aging and increase your risk for non-melanoma skin
cancers like basal and squamous cell cancers.
Once you reach this point your body will not make any additional vitamin
D and any additional exposure will only cause harm and damage to your
skin.
Most people with fair skin will produce the maximum amount of vitamin D
in just 10-20 minutes, or, again, when your skin starts turning the
lightest shade of pink. Some will need less, others more. The darker
your skin, the longer exposure you will need to optimize your vitamin D
production. African-Americans need perhaps 20 percent more sun exposure
time than whites.
And contrary to popular opinion, your body simply cannot make adequate
vitamin D from the sun unless you have more skin area exposed than just
your face and hands. In fact, at least 40 percent of your body should be
uncovered to optimize your vitamin D production.
Another option is to use a safe tanning bed, again paying attention to
not getting burned.
New Way to Protect Against Sunburn
A few months ago I found out that a carotenoid extracted from algae
called astaxanthin can be extremely useful in preventing and eliminating
sunburn. Interestingly, this is the antioxidant in krill that prevents
it from being damaged.
What current research is showing is that if you are on 2 mg of
astaxanthin for a month, it becomes very difficult to get sunburned.
Additionally, it also appears to prevent the development of the most
common form or blindness, age-related macular degeneration, as well as
cataracts, and most likely protects you from EMF when you are flying or
being exposed to diagnostic X-rays.
The key though is that it takes weeks to build up in your tissues, so
you can’t just swallow a few pills prior to your exposure and expect to
receive any benefit. Astaxanthin is also fat soluble and needs to be
taken with some fat or you simply won’t absorb it.
Vitamin D Supplements: How Much Should You Take?
It is wise to consider oral vitamin D3 supplementation during the winter
months, or year-round if you haven’t time or sufficient access to the
sun or a safe tanning bed.
However, the Reuter’s article above is years behind the research on
their recommended dosage of 1,000 IU’s a day
It’s true, there are no definitive studies on the optimal daily dose of
vitamin D, but based on studies on healthy indigenous peoples, many
vitamin D experts now agree that most adults, including pregnant women,
require about 5,000 IU of vitamin D daily for optimal health – or 35
IU’s of vitamin D per pound of body weight, which is certainly well
above the current RDA.
That said, although these recommendations may put you closer to the
ballpark of what most people likely need, it is impossible to make a
blanket recommendation that will cover everyone’s needs.
The ONLY way to determine how much you might need is by testing your
blood level of vitamin D.
This is in fact a very important aspect of optimizing your vitamin D
levels that you should not skip over.
Why?
Because while overdosing on vitamin D from sun exposure is highly
unlikely as your body has a built-in “failsafe” feedback loop, which
will tend to shut down production when your levels are healthy, it
IS possible to overdose when taking supplements.
So you need to be careful when using oral vitamin D therapy and
make certain you have your blood levels checked. Many of you may
choose to ignore this warning, but I am telling you in no uncertain
terms that while vitamin D has enormous potential for improving your
health, it has significant potential to worsen it, if you use it
improperly.
What Vitamin D Level do You Need to Stay Healthy?
The OPTIMAL value of vitamin D that you’re looking for has recently
been raised to 50-70 ng/ml, with even higher recommended levels
required for more serious disease prevention.
I hope you can see now some of the many benefits of vitamin D,
and why it is so critical to make sure you and your family maintain
healthy levels at all times.
Please take this opportunity to use one -- or more -- of the options
I’ve suggested for getting your daily dose of vitamin D. Optimal
vitamin D, however you get it, can literally make the difference
between a lifetime of chronic disease and one of vibrant health and
vitality.
Vitamin D Facts
Doctors are changing their minds about getting out in the sun. Getting
sun exposure a few minutes a day at least 3 times a week can be very
healthy. Vitamin D deficiency is being linked to a host of diseases that
might be prevented with proper sun exposure, supplements, or fortified
meals.
The Vitamin
D Battle - Recent government recommendations have increased the
daily recommended guidelines for vitamin D, but still some doctors argue
for higher daily intakes.