According to the page on astaxanthin on wikipedia -
Astaxanthin is a carotenoid. It belongs to a larger class of
phytochemicals known as terpenes. It is classified as a xanthophyll,
which means "yellow leaves". Like many carotenoids, it is a colorful,
lipid-soluble pigment. Astaxanthin is found in microalgae, yeast,
salmon, trout, krill, shrimp, crayfish, crustaceans, and the feathers of
some birds. Professor Basil Weedon was the first to map the structure of
astaxanthin.
Astaxanthin, unlike some carotenoids, is not converted to vitamin A
(retinol) in the human body. Too much vitamin A is toxic for a human,
but astaxanthin has lower toxicity. It is an antioxidant with a slightly
lower antioxidant activity than other carotenoids.
While astaxanthin is a natural nutritional component, it can also be
used as a food supplement. The supplement is intended for human, animal,
and aquaculture consumption. The commercial production of astaxanthin
comes from both natural and synthetic sources.
Currently, the primary use for humans is as a food supplement. Research
shows that due to astaxanthin's potent antioxidant activity, it may be
beneficial in cardiovascular, immune, inflammatory and neurodegenerative
diseases. Some research has suggested potential as an anti-cancer agent.
Research supports the assumption that it protects body tissues from
oxidative damage.
Doctor Mercola has posted a new article on astaxanthin. He says a lot of
good things about it like that it helps protect skin from damage from
the sun.
Want to Look Younger? Take This Simple Supplement Every Day for 2
Weeks
By Dr. Mercola
Sunscreen in a pill?
Prevention of wrinkles, dry skin, age spots and freckles?
Reversing the visible signs of aging?
If you think checking "all of the above" seems too good to be true,
you're not alone.
But there just happens to be a natural compound that clinical studies
are suggesting does ALL of the above—without a hefty price tag or side
effects. This is a little miracle your plastic surgeon won't want you to
hear about.
It's a relatively unknown carotenoid called astaxanthin, which is now
believed to be the most potent antioxidant nature has to offer.
Scientists long ago discovered that a class of naturally occurring
pigments called carotenoids held powerful antioxidant properties that
are crucial for your health. Carotenoids are the compounds that give
foods their vibrant colors—from green grasses to red beets, to the
spectacular yellows and oranges of your bell peppers.
There are more than 700 naturally occurring carotenoids, but most people
are familiar with only a few. Right now, you probably have about ten
different carotenoids circulating through your bloodstream.
As a source of antioxidants and vitamin A, carotenoids are critical to
the photosynthetic process and protect a plant or organism from damage
by light and oxygen. By consuming plants or organisms that contain these
pigments, you gain a similar protective benefit.
Astaxanthin has recently jumped to the front of the line in terms of its
status as a "supernutrient," becoming the focus of a large and growing
number of peer-reviewed scientific studies.
One of the benefits of astaxanthin that has piqued the interest of
researchers is its ability to help protect your skin from the sun,
reducing the signs of aging.
However, ataxanthin's benefits to your health are more than skin deep—in
fact, so many benefits that I've had to write several articles just to
cover the jaw-dropping activities of this amazing nutrient.
Astaxanthin is in a League of Its Own
Astaxanthin is produced only by the microalgae Haematoccous pluvialis
when its water supply dries up, forcing it to protect itself from
ultraviolet radiation. It's the algae's survival mechanism—astaxanthin
serves as a "force field" to protect the algae from lack of nutrition
and/or intense sunlight.
It is this "radiation shield" that underlies how astaxanthin can help
protect you from similar radiation.
Many carotenoids are easily obtainable through a good diet rich in fresh
organic produce. However, this powerful carotenoid is harder to come by.
There are only two main sources of astaxanthin—the microalgae that
produce it, and the sea creatures that consume the algae (such as
salmon, shellfish, and krill).
Astaxanthin is the reason salmon have the strength and endurance to swim
up rivers and waterfalls for days on end—their diets are high in this
pigment, which concentrates in their muscles and makes them one of the
"kings of endurance" of the animal kingdom.
This pigment is the most commonly occurring red carotenoid in marine and
aquatic animals and is what gives salmon and pink flamingos their
characteristic pink color. Most people don't realize that baby flamingos
are actually white and don't turn pink until they receive astaxanthin,
primarily from shrimp and algae.
Astaxanthin is leaps and bounds more powerful than beta-carotene, alpha-tocopherol,
lycopene and lutein, other members of its chemical family. It exhibits
VERY STRONG free radical scavenging activity and protects your cells,
organs and body tissues from oxidative damage.
Astaxanthin's unique "antioxidative artillery" provides for an
impressive array of health benefits, including improving cardiovascular
health, stabilizing blood sugar, boosting your immune system, fighting
cancer, reducing inflammation, improving eye health—and even improving
your athletic abilities.
What Makes Astaxanthin Special?
There are many properties that make this carotenoid unique. Here are the
main differences:
Astaxanthin is by far the most powerful carotenoid antioxidant when it
comes to free radical scavenging: astaxanthin is 65 times more powerful
than vitamin C, 54 times more powerful than beta-carotene, and 14 times
more powerful than vitamin E.
Astaxanthin is far more effective than other carotenoids at "singlet
oxygen quenching," which is a particular type of oxidation. The damaging
effects of sunlight and various organic materials are caused by this
less-stable form of oxygen. Astaxanthin is 550 times more powerful than
vitamin E and 11 times more powerful than beta-carotene at neutralizing
singlet oxygen.
Astaxanthin crosses the blood-brain barrier AND the blood-retinal
barrier (beta carotene and lycopene do not), which brings antioxidant
and anti-inflammatory protection to your eyes, brain and central nervous
system and reduces your risk for cataracts, macular degeneration,
blindness, dementia and Alzheimer's disease.
Astaxanthin is soluble in lipids, so it incorporates into cell
membranes.
It's a potent UVB absorber and reduces DNA damage.
It's a powerful natural anti-inflammatory.
And how about some more great news? There have been no adverse reactions
found for people taking astaxanthin.
Sunburn is Inflammation
If you are physically active, you have probably spent a fair amount of
time in the sun. The sun offers enormous benefits to you in terms of
vitamin D. But too much of a good thing can be—well, too much of a good
thing.
Many athletes complain of feeling ill from overexposure to the sun after
long trainings outside. However, many report astaxanthin has allowed
them to stay in the sun for longer periods of time, without feeling ill
and without burning. Less burning also means lower skin cancer risk.
How does it do this?
The answer lies in how the Haematoccous pluvialis protects itself from
intense ultraviolet radiation by producing astaxanthin as a natural
sunscreen. When you consume this pigment, you are creating your own
"internal sunscreen." In other words, the same powerful antioxidants
that protect the algae from the sun's rays can help protect YOU as well.
Sunburn is actually an inflammatory process. Although the exact pathway
by which astaxanthin protects your skin from burning is not yet known,
it is almost certain that its anti-inflammatory properties are involved.
Dr. Nicholas Perricone and Dr. Robert Childs, a physician in Hawaii, are
both fans of astaxanthin.
Dr. Childs, born and raised in Honolulu, was always extremely sensitive
to the sun, until he started taking astaxanthin. He now finds he can go
out in the midday Hawaiian sun for four hours without burning, whereas
he used to burn within a half hour. He also discovered that, within a
few weeks of starting astaxanthin, his morning stiffness and soreness
had disappeared.
Astaxanthin as an Internal Sunscreen
Besides copious testimonials and anecdotal evidence, scientific studies
have substantiated these skin protective effects.
Cyanotech Corporation funded a study through an independent consumer
research laboratory to measure the skin's resistance to both UVA and UVB
light, before and after astaxanthin supplementation.
The result was that in only three weeks of taking 4mg per day, subjects
showed a significant increase in the amount of time necessary for UV
radiation to redden their skin.
Animal studies lend further evidence to astaxanthin's effects as an
internal sunscreen.
Consider the following:
In 1995, hairless mice were fed various combinations of astaxanthin,
beta-carotene and retinol for four months. After irradiation,
astaxanthin alone or in combination with retinol was substantially
effective in preventing photoaging of the skin (as measured by markers
for skin damage). [Savoure, N., Briand, G., Amory-Touz, M., Combre, A.,
Maudet, M. (1995). "Vitamin A status and metabolism of cutaneous
polyamines in the hairless mouse after UV irradiation: action of
beta-carotene and astaxanthin." International Journal for Vitamin and
Nutrition Research. 65(2):79-86.]
In a 1998 study with rats, astaxanthin was found to be 100 times
stronger than beta-carotene and 1000 times stronger than lutein in
preventing UVA light-induced oxidative stress.
The Journal of Dermatological Science published a study in 2002 finding
astaxanthin is able to protect against alterations in human DNA induced
by UVA light exposure.
A Topical Paradise: Help in Preventing Collagen Damage, Wrinkles,
Freckles and Age Spots
But astaxanthin might not even need to be ingested in order to protect
you from the sun. In 2001, Arakane performed a study on hairless mice to
explore whether or not astaxanthin offered topical benefits.
The mice were exposed to UVB radiation for 18 weeks to simulate
photo-aged skin. The mice that had astaxanthin applied to their skin
demonstrated reduced wrinkles when compared to the control group, as
well as younger-appearing collagen. In fact, the collagen of the
astaxanthin mice looked as if it had never been exposed to radiation.
Researchers concluded that astaxanthin "can significantly prevent
UV-induced collagen degradation, wrinkles, lipid peroxidation, sunburn,
phototoxicity and photoallergy."
The same study also discovered that topical astaxanthin can act as an
effective "skin whitening agent," which is a tremendously popular trend
in Asia. Astaxanthin was found to reduce melanin by 40 percent, greatly
reducing freckles and age spots.
Beauty From Within
Although it appears that astaxanthin does indeed offer topical benefits,
your greatest gifts will come from taking astaxanthin internally.
There have been three studies demonstrating that taking astaxanthin can
improve the way you look. All of these studies combine astaxanthin with
other substances, such as omega-3 fatty acids or vitamin E, but all
three had positive findings when astaxanthin was present.
In Japan, a study was done in 2002 by Yamashita with women around age 40
who consumed 2mg astaxanthin daily for four weeks. Researchers were
surprised that after only 2 weeks, almost every aspect of the women's
skin had improved; after 4 weeks, there was even more improvement.
[Yamashita, E. (2002). "Cosmetic Benefit of Dietary Supplements
Containing Astaxanthin and Tocotrienol on Human Skin." Food Style. 21
6(6):112-17]
Benefits included fewer fine lines, better moisture, increased skin tone
and elasticity, smoother surface, fewer freckles, and less under-eye
puffiness.
In 2003 a Canadian study involving female subjects ages 35 to 55 were
given astaxanthin combined with omega-3 fatty acids and marine
glycosaminoglycans. They were divided into three groups using different
combinations of these agents, all showing improvements in the areas
measured.
Due to the design of the study, researchers were limited in the
conclusions they could draw, but said it was clear that astaxanthin does
offer benefits as an internal beauty supplement.
The third study was done in Europe and was similar to the Japanese study
discussed above. However, subjects were given 5mg per day astaxanthin
along with two other ingredients. Treated subjects showed improvements
in fine lines, an increase in dermis density of up to 78 percent, and
visible improvement in overall skin appearance.
Can Eating Colorful Vegetables Make You MORE Attractive and Help Snag
You a Mate?
One of the most interesting studies to date was headed by Dr. Ian
Stephen at the University of Nottingham who investigated what skin tones
were perceived as most healthy and attractive to humans.
He discovered that red and yellow skin tones make you more attractive.
People take on redder tones when they are flushed with blood,
particularly if the blood has lots of oxygen in it, and from a
biological/anthropological perspective, this signals health and
vitality.
Scientists have believed that we evolved by selecting potential mates
whose appearance signaled good health. According to coauthor of the
study, David Perrett, PhD:
"This is something we share with many other species. For example, the
bright yellow beaks and feathers of many birds can be thought of as
adverts showing how healthy a male bird is. What's more, females of
these species prefer to mate with brighter, more colored males. But this
is the first study in which this has been demonstrated in humans.
Together our studies link skin carotenoid coloration to both perceived
health and healthy diet, establishing carotenoid coloration as a valid
cue to human health which is perceptible in a way that is relevant to
mate choice, as it is in bird and fish species."
Healthier Looking Than a Tan !!
And here's the kicker...
Dr. Stephen found that, given the choice between skin color caused by
suntan and skin color caused by carotenoids, people preferred the
carotenoid skin color.
So if you want to be more physically attractive, make sure you use a
regular source of astaxanthin. Not only will it allow you to look
healthier it will also help protect you when you are tanning and
optimizing your vitamin D levels.
Make Sure Your Astaxanthin is the Natural Variety from Marine Algae—NOT
Synthetic
Synthetic (laboratory-made) astaxanthin is now commonly used worldwide
to supplement fish feeds in order to obtain the desired pinkish to
orange-red color. You really should avoid synthetic astaxanthin because
it's made from petrochemicals.
Some aquaculture companies are beginning to use natural astaxanthin
instead of synthetic, even though it costs more, because it's better for
the health of the animals, and it's far superior for pigmentation.
Animals fed fish food with natural astaxanthin have higher survival
rates, better growth rates, better immunity, fertility and reproduction.
Unfortunately, synthetic astaxanthin still dominates the farmed salmon
industry worldwide.
If your salmon label does not read "wild" or "naturally colored," you're
probably going to be eating a coloring agent somewhat closer to motor
oil than antioxidant. Natural astaxanthin is more than 20 times stronger
as an antioxidant than synthetic astaxanthin.
Wild salmon are 400 percent higher in astaxanthin than farmed salmon,
and100 percent of their pigment is natural astaxanthin, rather than
synthetic. Plus, wild salmon have much higher levels of omega-3 fatty
acids than the farmed version. But even if you are successful in
purchasing genuine wild salmon, there is the problem with high levels of
mercury and other unwanted toxins, not to mention the skyrocketing
prices.
Final Recommendations
If you decide to give astaxanthin a try, I recommend starting with at
least 2 mg per day. I have been taking 8 mg per day this year. Krill has
some astaxanthin in it, but not enough to provide full benefits.